the antihistamine piperoxan was synthesized using the reaction of catechol and epichlorohydrin in the presence of sodium page 708 hydroxide as the first step. write a mechanism for this reaction

Answers

Answer 1

The base will first cause one of the OH groups to deprotonate before the nucleophile (O⁻) attacks the epichlorohydrin.

What is sodium hydroxide is used for?

Manufacturers use the chemical sodium hydroxide to create products including soap, viscose, paper, explosives, pigments, and petroleum. Other applications for sodium hydroxide include the processing of cotton fibers, metal cleansing and treatment, oxidation coating, plated, and electrochemical extract.

Briefing:

A) The base will first cause one of the OH groups to deprotonate before the nucleophile (O⁻) attacks the epichlorohydrin.

B)The second OH group will once more deprotonate, and the H2 molecule will likewise be eliminated from the epichlorohydrin. Then, the nucleophile (O⁻) will attack the carbocation internally.

C)Alkyl halide hydrolysis produces primary alcohol.

D) Following another round of dehydrolysis, piperidine and carbocation react to produce piperoxan.

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Related Questions

Metals can be protected from corrosion by applying a coating that protects the metal by acting as a barrier. Painting is one way of applying a coating. Give the other TWO.

Answers

The ways in which metals can be protected from corrosion include the following below:

Cathodic protectionCorrosion inhibitors.

What is Corrosion?

This is common with metals and is a process which occurs as a result of its exposure to the surroundings. This results in metals forming a stable oxide thereby leading to the deterioration of the material.

There are however several ways to protect them from corrosion such as painting and the use of corrosion inhibitors such as chromates etc which helps to coat it and prevent the oxidation process from occurring thereby making it the correct choice.

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If a 22.4 L volume of a sample of gas has a density of 0.900 grams/L at 1.00 atm and 0.00°C. Given
the following gases, which could it be?
A. Ne
B. CO
C. CO2
D. Kr

Answers

Answer:

Formula Weight of gas sample = 20.1 g/mole => Neon (Ne)

Explanation:

Use Ideal Gas Law formula to determine formula weight and compare to formula weights of answer choices.

PV = nRT = (mass/fwt)RT => fwt = (mass/Volume)RT = Density x R x T

Density = 0.900 grams/L

R = 0.08206 L·atm/mole·K

T = 0.00°C = 273Kfwt = (0.900g/L)(0.08206L·atm/mole·K )(273K)

= 20.1 g/mol => Neon (Ne)

15. The half-life of Rn-222 is 3. 823 days. What was the original mass of Rn if 0. 05 grams remain after 7. 646 days?

Answers

The original mass of Rn-222 was 0.2 grams.

The quantity of substance in an item or system is measured by its mass, which is a fundamental physical attribute of matter. It is a measurement of an object's resistance to changes in motion and is often expressed in kilogram (kg) or gram (g) units. It's common to conflate weight—the force of gravity acting on an object—with mass. However, weight varies according to the strength of the gravitational field, whereas mass is constant no matter what gravitational field it is in.

The decay of Rn-222 can be modeled using the following equation:

N(t) = N₀ ×  \(\frac{1}{2} ^\frac{t}{T}\)

where N(t) is the amount of Rn-222 remaining at time t, N₀ is the initial amount of Rn-222, T is the half-life of Rn-222, and  \(\frac{1}{2} ^\frac{t}{T}\) is the fraction of  Rn-222 remaining after time t.

We are given that the half-life of Rn-222 is 3.823 days and that 0.05 grams remain after 7.646 days. Using the equation above, we can set up the following equation:

0.05 grams = N₀ × \(\frac{1}{2} ^ \frac{7.646}{3.823}\)

Solving for N₀, we get:

N₀ = 0.05 grams /  \(\frac{1}{2} ^ \frac{7.646}{3.823}\)

N₀ = 0.05 grams / 0.5²

N₀ = 0.05 grams / 0.25

N₀ = 0.2 grams

Therefore, the original mass of Rn-222 was 0.2 grams.

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CAN YOU PLEASE ANSWER
Which observations describe both images? Select all the correct answers. The oil mixes with water. The oil floats on the surface of the water. The oil sinks to the bottom of the water. The oil spreads to cover the water. The oil stays in one spot.

Answers

Answer:

the oil spreads to cover the water

Answer:

I think it is ; The oil floats to the surface of the water

Explanation:

I don't know about the other one.

Which of the following is not related to metallic bond?
A. Alloy
B. Shared electrons
C. Transferred electrons
D. Sea of electrons

Answers

Answer: B. Shared electrons

Explanation: Electrons are shared in covalent bonds. The other options are all properties of metallic bonds.

why is the first ionization energy (i.e.) for mg greater than that for na? why is the second i.e. so much greater for na than for mg?

Answers

The first ionization energy of magnesium is larger than that of sodium because magnesium has one more proton present in its nucleus to hold on to the electrons in the 3s orbital.

First ionization energy is defined as the energy that is required to remove the first electron from a neutral atom. First ionization energy is numerically same as the orbital energy of the electron but it is of opposite sign.

The second I.E is so much greater for Na than for Mg because after losing its one electron it becomes more stable by attaining noble gas configuration and hence more enthalpy is required to remove an electron from the stable atom.

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Litharge, PbO, is an ore that can be roasted (heated) in the presence of carbon monoxide, CO, to produce elemental lead. The reaction that takes place during this roasting process is represented by the balanced equation below.

In which compound does carbon have the greater oxidation number?

Answers

Thus, in this reaction, carbon has a greater oxidation number of +2 in carbon monoxide (CO) compared to its oxidation number of zero in elemental lead (Pb).

In the reaction where litharge (PbO) is roasted in the presence of carbon monoxide (CO) to produce elemental lead, the carbon in carbon monoxide has a greater oxidation number compared to carbon in elemental lead.

In carbon monoxide (CO), the oxidation number of carbon is +2. This is because oxygen generally has an oxidation number of -2, and since the compound is neutral, the sum of the oxidation numbers must be zero. Therefore, the oxidation number of carbon in CO is calculated as: (+2) + (-2) = 0.On the other hand, in elemental lead (Pb), the oxidation number of carbon is zero. This is because elemental substances are considered to have an oxidation number of zero.The oxidation number reflects the electron distribution and the transfer of electrons during a chemical reaction, providing insights into the reactivity and bonding of the elements involved.

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is soda homogeneous or heterogeneous? ​

Answers

Answer:

Thecinically it is both because and  an un opened bottle of soda is homogeneous and an opened bottle of soda is herterogeneous. I hope this helps please reward branlist.

true or false: in major keys, the tonic, subdominant, and dominant triads are major.

Answers

True. In major keys, the tonic (I), subdominant (IV), and dominant (V) triads are major.

This is because the major scale follows a specific pattern of whole and half steps, and the tonic, subdominant, and dominant notes fall on the first, fourth, and fifth scale degrees respectively.

When these notes are harmonized to form triads, they naturally result in major chords. However, it's important to note that in minor keys, the subdominant and dominant triads are often different (minor or diminished) than in major keys.
True, in major keys, the tonic, subdominant, and dominant triads are major. In a major key:

1. Tonic triad (I) is formed using the 1st, 3rd, and 5th scale degrees and is major.
2. Subdominant triad (IV) is formed using the 4th, 6th, and 1st scale degrees and is also major.
3. Dominant triad (V) is formed using the 5th, 7th, and 2nd scale degrees and is major as well.

These three triads are crucial in establishing the tonality of a major key and are all major in quality.

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Draw the principal organic product expected when 2-methylthiophene reacts with hno3. show minimized formal charges, if applicable.

Answers

Answer:

2-Methyl-5-nitrothiophene  

Explanation:

The 2- and 5-positions of thiophene are the most susceptible to electrophilic aromatic substitution.

Thus, the major product from the reaction of 2-methylthiophene with HNO₃ in acetic acid is 2-methyl-5-nitrothiophene.

Draw the principal organic product expected when 2-methylthiophene reacts with hno3. show minimized formal

PLEASE HELP!!! Consider the reaction pathway graph below. Image Which letter represents the activated complex? A B F G

PLEASE HELP!!! Consider the reaction pathway graph below. Image Which letter represents the activated

Answers

Answer : The letter represents the activated complex is, B.

Explanation :

Activated complex : When the reactant molecules absorb energy, their bonds are loosened and new loose bonds are formed between them.

The intermediate thus formed is known as an activated complex or it is also known as transition state complex.

It is unstable and immediately dissociates to form the stable products. In the graph, it is present at the higher point.

In the given graph, F represent the reactant energy, B represent the activated complex, G represent the product, Y represent the reactant, C energy of the reaction.

Hence, the activated complex is located at point B.

Answer:

b

Explanation:

Which identifies an oxidation-reduction reaction?
a double replacement reaction
a neutralization reaction
a reaction in which oxidation numbers change
a reaction in which no electrons are transferred

Answers

The statement that identifies an oxidation-reduction reaction is a reaction in which oxidation numbers change (option C).

What is a redox reaction?

A redox or oxidation-reduction reaction is a chemical reaction in which some of the atoms have their oxidation number changed.

In a chemical reaction that involves oxidation and reduction, the oxidation number of the involved ions either decreases or increases.

Therefore, the statement that identifies an oxidation-reduction reaction is a reaction in which oxidation numbers change.

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F it takes 0.0500 l of oxygen gas kept in a cylinder under pressure to fill a 4.00 l vessel in which the pressure is 0.980 atm, what was the initial pressure of the gas in the cylinder

Answers

Answer:

0.012atm pressure

Explanation:

pressure is inversly proportional to volume. Mathematically,

V1/P1=V2/P2

Which of the following is the best way to model the process of weathering?

Using a fan on a pile of sand causing the sand to move into a pile in a new location.

Using a ramp to dump sand at the bottom causing the sand to pile up.

Using a watering can sprinkle water onto sand causing the sand to move to a new location.

Filling a glass bottle with water and allowing it to freeze causing the bottle to break.

Answers

i think it’s the last one

The best model of weathering is using a fan on a pile of sand causing the sand to move into a pile in a new location.

Weathering refers to the gradual breakdown of a rock due to the agents of denudation. The agents of denudation could be physical, chemical or biological.

The breakdown of rocks leads to the formation of soil. The closest model to the weathering of rock is using a fan on a pile of sand causing the sand to move into a pile in a new location.

The pile represents the rock which is being broken down as the fan blows the pile and it settles on a new location.

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I need help with this someone help

I need help with this someone help

Answers

Answer:

1. Element is Ca

2. 20 electrons

3. 2 valence electrons

4. 4 energy levels

the combustion of carbon disulfide with oxygen forms carbon dioxide and sulfur dioxide. what are the coefficients when the reaction equation is balanced using the simplest, whole number coefficients? the pink spheres represent sulfur atoms, the black spheres carbon atoms and the open spheres, oxygen atoms.

Answers

Fuel consumption and other atoms than carbon and hydrogen, such as sulfur, nitrogen, or oxygen, have a direct impact on carbon dioxide emissions.

What is the carbon combustion equation in words?

Charcoal, a solid, and oxygen, a gas, are the reactants in the described reaction, and carbon dioxide gas is the result. It is possible to write the chemical equation as C (s) + O2 (g) CO2 (g) Q.

Carbon combustion is what kind of a reaction?

Since heat is produced during the reaction, it is an exothermic reaction. As carbon and oxygen combine to generate carbon dioxide, it is a combination reaction. It is a combustion reaction because oxygen causes carbon to burn.

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What state of matter has particles that are close together but can slide past each other.

Answers

The particles in a liquid are also attracted to each other, but not as strongly as in a solid. The particles are close together, moving constantly, and can slide past one another.

What is Liquid ?A liquid is a nearly incompressible fluid that, regardless of pressure, takes on the shape of its container while maintaining an even volume. It is one of the four fundamental states of matter because it is the only one with a fixed volume but no fixed shape.Coolants, solvents, and lubricants are all examples of liquids. Tribology studies liquids for their lubricating properties.Oil and other lubricants are chosen for their viscosity and flow properties over the component's entire working temperature range.Surface tension, capillary action, and viscosity are all properties of liquids that are influenced by intermolecular interactions. Surface tension is the amount of energy required to increase the surface area of a liquid by a specific amount.

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What is the concentration in ppm of a solution which is prepared by dissolving 15 mg of NaCl in 200 mL water? Assume that the volume does not change after the solution formation. (1 ppm = 1 mg/L) a75 b.15 c.7.5 x 10^-5
d.1.5 x 10^-5 e,0.075

Answers

The concentration of a solution that is prepared by dissolving 15 mg of NaCl in 200 mL water is 75 ppm. So, the correct option is a.

To calculate the concentration in parts per million (ppm), we need to determine the amount of NaCl dissolved in the solution and then convert it to ppm.

Mass of NaCl = 15 mg

Volume of solution = 200 mL

First, we need to convert the volume from milliliters (mL) to liters (L):

Volume of solution = 200 mL = 200/1000 L = 0.2 L

Next, we can calculate the concentration of NaCl in mg/L:

Concentration (mg/L) = (mass of solute in mg) / (volume of solution in L)

Concentration (mg/L) = 15 mg / 0.2 L = 75 mg/L

Finally, we can convert the concentration from mg/L to ppm:

Concentration (ppm) = Concentration (mg/L) = 75 ppm

Therefore, the concentration of the NaCl solution is 75 ppm, which corresponds to option (a).

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Zinc- nickel single flow batteries with improved cycling stability by eliminating zinc accumulation on the negative electrode. Electrochim. Acta 145, 109–115. doi:

Answers

Zinc- nickel single flow batteries with improved cycling stability by eliminating zinc accumulation on the negative electrode. Electrochim. Acta 145, 109–115. doi: Zinc accumulation is recognized as one of the most critical issues that affect the cycle life of zinc-nickel single flow batteries (ZNBs).

What is Zinc- nickel?

High performance zinc-nickel coatings provide superior corrosion resistance, especially for items used in challenging situations.

A special composition that will corrode less quickly than zinc alone is produced by alloying nickel and zinc. This alloy coating, with a composition of roughly 10-15% nickel and the remaining zinc, can offer up to ten times the protection of traditional zinc plating.

Due to considerations including extended product warranties, longer life cycle requirements, stricter safety regulations, and decreased environmental effect, there is an increased demand for Zinc Nickel Large across sectors. Following applications commonly call for zinc-nickel:

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Convert the following 2856 m(meters) to km(kilometers)Immersive Reader
a. 2,856,000 km
b. 2.956 km
c. 28.56 km
d. 0.02856 km

Answers

Answer: 2.856km

Explanation: 1000m = 1km

2856m / 1000 = 2.856km

4. The representative particle for an ionic compound is a​

Answers

Answer:

unit formula??

Explanation:

Which are three ways water reaches the atmosphere?
A. sublimation, condensation, transpiration
B. evaporation, radiation, and condensation
C. transpiration, evaporation, and sublimation

Answers

Answer:

C. Transpiration, evaporation, and sublimation.

Explanation:

thank you to the internet.

C .....................

describe the costs and benefits of aliasing, and explain how it can be avoided.

Answers

Aliasing is a significant issue in the fields of computer graphics, signal processing, and audio processing.

Here are the costs and benefits of aliasing and how to avoid it .Benefits of Aliasing The main benefit of aliasing is that it reduces the amount of data needed to represent an image, signal, or sound, resulting in lower costs for storage and processing. Costs of Aliasing The primary cost of aliasing is that it can cause distortions in the image, sound, or signal that are being represented. This may result in a loss of image or sound quality. In some cases, it can even cause the signal to become completely unintelligible.

This is particularly true when the signal has a high frequency, which is prone to aliasing.

Explanation of how to Avoid Aliasing To avoid aliasing, the following steps should be taken:

Under sampling: It refers to the act of sampling a signal at a lower rate than the Nyquist frequency. As a result, the signal is not reconstructed properly, resulting in aliasing. Therefore, the sampling rate must be increased.

Oversampling: It refers to the act of sampling a signal at a higher rate than the Nyquist frequency. In oversampling, a signal is sampled at a higher frequency than its maximum frequency, which eliminates aliasing.Noise Shaping: It is a technique that reduces noise levels in digital signals. This process involves adding noise to the signal before quantizing it.

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Aqueous zinc bromide reacts with solid aluminum to produce aqueous aluminum bromide and solid zinc. Write a balanced equation for this reaction

Answers

The balanced equation for the reaction between aqueous zinc bromide (ZnBr₂) and solid aluminum (Al) to produce aqueous aluminum bromide (AlBr₃) and solid zinc (Zn) is:

3ZnBr₂ + 2Al -> 2AlBr₃ + 3Zn

In this reaction, three moles of zinc bromide (ZnBr₂ ) react with two moles of aluminum (Al) to yield two moles of aluminum bromide (AlBr₃) and three moles of zinc (Zn). The equation is balanced in terms of both mass and charge, ensuring that the number of atoms of each element is the same on both sides of the equation.

This reaction represents a single replacement or displacement reaction, where aluminum replaces zinc in the compound to form a new compound and release zinc as a solid product.

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3.0 mol of NaOH is dissolved in 2.5 L of water, what is the
molarity of the solution?
A. 120 M
B. 40 M
C. 3M
D. 1.2 M

Answers

It is D i think because of the question

Zns (zinc sulfide) (Zn = 65.38; S = 32.06] *

Answers

The question is incomplete, the complete question is;

Zinc and sulfur react to form zinc sulfide by the equation shown below. How many grams of ZnS can be formed when 12.0 g of Zn reacts with 6.50 g of S? (Atomic mass: Zn = 65.38, S = 32.06).

Answer:

17.5 g of ZNS

Explanation:

The equation of the reaction is;

Zn(s) + S(s) ------->ZnS(s)

Number of moles of Zn = 12.0/65.38 = 0.18 moles

Number of moles of S = 6.50/32.06 = 0.20 moles

Hence Zn is the limiting reactant

If 1 mole of Zn yields 1 mole of ZnS

Then 0.18 moles of Zn also yields 0.18 moles of ZnS

Mass of ZnS produced = 0.18 moles *  97.44 g/mol = 17.5 g of ZNS

Answer:

17.5 g of ZNS

Explanation:

what the function of the male reproduction system called scrotum​

Answers

Answer:

The bag of skin that holds and helps to protect the testicles. The testicles make sperm

Explanation:

name the harmful by products formed by the burning of diesel and coal​

Answers

Burning of diesel and coal produces a suffocating and corrosive gas-Sulphur dioxide gas, and Petrol engines give off gaseous oxides of nitrogen. Oxides of these sulphur and nitrogen dissolves in rain water and causes Acid Rain

Answer:

Burning of coal and diesel release sulphur dioxide gas. It is an extremely suffocating and corrosive gas. Sulphur dioxide and nitrogen oxide dissolve in rain water to form acid. Such rain is called acid rain.

Explanation:

mercury thermometer should not be placed in the mouth of the children why?​

Answers

Answer: If a pinch of mercury is consumed you will die from it so using a mercury thermometer is very unsafe if its breaks and a child consumes that mercury.

Explanation:

Don't use one

If the glass breaks and the mercury is not properly cleaned up, the little silvery ball within a mercury thermometer might be hazardous. As the mercury evaporates, it may pollute the air around and turn dangerous to both people and animals.

Children that have been exposed to mercury have lower IQs, hearing impairments, and worse coordination.

Long-term exposure worsens and exacerbates symptoms, which may lead to personality changes or even coma.

Mercury thermometers can be replaced by a number of things:

electronic thermometersGlass thermometers with gallium tinalcohol thermometers in glass

These non-mercury fever thermometers are significantly safer and equally accurate as mercury thermometers.

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Explain how you would dilute a 1 mol/dm solution to one-tenth of its original
concentration.​

Answers

Answer:

13.123.

Explanation:

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